MOTS-c

Product Summary Table

Name	MOTS-c
Molar Mass	1636.88 g/mol
Chemical Formula	C47H75N13O15S
IUPAC Name	L-methionyl-L-arginyl-L-tyrosyl-L-phenylalanyl-L-tyrosyl-L-leucyl-L-arginyl-L-tryptophyl-L-leucyl-L-threonyl-L-glutaminyl-L-glutamyl-L-glutaminyl-L-alanyl-L-valyl-L-prolyl
Synonyms	Mitochondrial Open Reading Frame of the 12S rRNA Type-c, MOTS peptide
Country of Origin	USA
Storage	Reconstituted peptide should be stored between 1–4°C and kept away from direct light.
Standard	Research Purity ≥99%

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a naturally occurring mitochondrial-derived peptide available for research through VI Corpus. This peptide has gained scientific attention for its role in regulating cellular metabolism, promoting mitochondrial efficiency, and enhancing glucose utilisation. Through the activation of the AMPK pathway, MOTS-c contributes to improved energy homeostasis and metabolic performance, making it a key compound for studies related to longevity, obesity, and insulin sensitivity.

In Vivo Research Benefits

• Regulates Energy and Metabolism: MOTS-c enhances mitochondrial function and supports balanced cellular energy metabolism, helping researchers explore mechanisms of metabolic adaptation and endurance.
• Improves Glucose Utilisation: Scientific studies have shown that MOTS-c influences glucose uptake and insulin sensitivity, offering insights into metabolic disease and obesity research.
• Supports Fat Reduction: By activating AMPK and promoting lipid metabolism, MOTS-c has been observed to assist in fat breakdown and energy conversion during research trials.
• Enhances Exercise Performance: Animal studies suggest improved exercise tolerance and recovery through MOTS-c’s mitochondrial support and improved energy production.
• Longevity and Cellular Health: As a mitochondrial-derived peptide, MOTS-c is linked to research into ageing, oxidative stress resistance, and mitochondrial biogenesis.

Dosage and Administration

• Dosage: 10mg / vial.
• Form: Lyophilised peptide for reconstitution.
• Usage: For in vivo research use only. Reconstituted MOTS-c should be administered according to standard peptide research protocols under controlled laboratory conditions. Typical experimental parameters involve studying its effects on AMPK activation, mitochondrial biogenesis, and metabolic regulation.

Studies and Additional Info

• https://pmc.ncbi.nlm.nih.gov/articles/PMC9905433/
• https://www.osti.gov/biblio/22598794